The 3D organ and tissue printing technique is an interdisciplinary field involving life sciences, biology, physics and engineering. Modern lifestyle has led to an increase in number of patients who require organ transplant because of diseases, congenital problems and accidents. However, the number of available organs for transplantation does not meet the ever increasing demand. Apart from shortage of organs, compatibility of tissues of donor and recipient is another issue involved in organ transplantation. Both the problems can be overcome by 3D organ and tissue printing technique. The 3D organ and tissue printing technique is a complex and sensitive technique which can print organs and tissues layer by layer by using the bio ink. Bio ink is sensitive to factors such as temperature, pressure and viscosity which affects the cell functioning. Manufacturing of artificial organs requires in depth knowledge of structure and tomography of the organ. In 2002, scientists (Wake Forest Institute for Regenerative Medicine) printed a miniature functional kidney capable of filtering blood and producing urine in an animal model. In 2009, Organovo — a bio-printing company headquartered in San Diego — printed the first Blood Vessel. Many organs have been created using 3D technology such as liver tissue, heart, eye cornea, bones etc. 3D organ and tissue printing market is growing rapidly and has been predicted to cross 10 billons by year 2022. Organ printing can be viewed as revolution in health care sector.